Ophiopogonin D maintains Ca(2+) homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/EETs and suppressing ER stress.

CONCLUSION: OPD is a novel CYP2J3 inducer that may offer a therapeutic benefit in treatment of cardiovascular diseases related to disturbance of Ca(2+) homeostasis and ER stress. PMID: 26838069 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26838069?dopt=Abstract

Source: Acta Pharmacologica Sinica - February 1, 2016 Category: Drugs & Pharmacology Authors: You WT, Zhou T, Ma ZC, Liang QD, Xiao CR, Tang XL, Tan HL, Zhang BL, Wang YG, Gao Y Tags: Acta Pharmacol Sin Source Type: research