PANCR, the PITX2 Adjacent Noncoding RNA, Is Expressed in Human Left Atria and Regulates PITX2c Expression [Original Articles]

Conclusions—
PANCR and PITX2c are coordinately expressed early during cardiomyocyte differentiation from stem cells. PANCR knockdown decreased PITX2c expression in differentiated cardiomyocytes, altering the transcriptome in a manner similar to PITX2c knockdown.

Source: Circulation: Arrhythmia and Electrophysiology - January 18, 2016 Category: Cardiology Authors: Gore-Panter, S. R., Hsu, J., Barnard, J., Moravec, C. S., Van Wagoner, D. R., Chung, M. K., Smith, J. D. Tags: Arrhythmias, Atrial Fibrillation, Gene Expression & Regulation, Functional Genomics Original Articles Source Type: research