Promoting tumor penetration of nanoparticles for cancer stem cell therapy by TGF-β signaling pathway inhibition.

This study suggests that enhanced tumor penetration of drug-carrying nanoparticles can enhance CSCs clearance in vivo and consequently provide superior anti-tumor effects.
PMID: 26751819 [PubMed - as supplied by publisher]

Source: Biomaterials - December 21, 2015 Category: Materials Science Authors: Zuo ZQ, Chen KG, Yu XY, Zhao G, Shen S, Cao ZT, Luo YL, Wang YC, Wang J Tags: Biomaterials Source Type: research