Seladin-1/DHCR24 Is Neuroprotective by Associating EAAT2 Glutamate Transporter to Lipid Rafts in Experimental Stroke [Basic Sciences]

Conclusions—
These results support the idea that lipid raft integrity, ensured by seladin-1/DHCR24, plays a crucial protective role in the ischemic brain by guaranteeing EAAT2-mediated uptake of glutamate excess.

Source: Stroke - December 28, 2015 Category: Neurology Authors: Hernandez-Jimenez, M., Martinez-Lopez, D., Gabande-Rodriguez, E., Martin-Segura, A., Lizasoain, I., Ledesma, M. D., Dotti, C. G., Moro, M. A. Tags: Cerebrovascular Disease/Stroke, Neuroprotectants Basic Sciences Source Type: research