Prenatal Exposure to Organophosphorous Pesticides and Fetal Growth: Pooled Results from Four Longitudinal Birth Cohort Studies

Conclusions: This study confirms previously reported associations of prenatal OP exposure among Black women with decreased infant size at birth, but finds no evidence of smaller birth weight, length, or head circumference among Whites or Hispanics. Contrary to our hypothesis, we found stronger inverse associations of DAPs and birth outcome in infants with the less susceptible PON1192RR genotype. The large pooled dataset facilitated exploration of interactions by race/ethnicity and PON1 genotype, but was limited by differences in study populations. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Harley KG, Engel SM, Vedar MG, Eskenazi B, Whyatt RM, Lanphear BP, Bradman A, Rauh VA, Yolton K, Hornung RW, Wetmur JG, Chen J, Holland NT, Barr DB, Perera FP, Wolff MS. Prenatal Exposure to Organophosphorous Pesticides and Fetal Growth: Pooled Results from Four Longitudinal Birth Cohort Studies. Environ Health Perspect; http://dx.doi.org/10.1289/ehp.1409362 Received: 17 October 2014 Accepted:...
Source: EHP Research - Category: Environmental Health Authors: Tags: Children's Health Source Type: research