Iron in Frontotemporal Lobar Degeneration: A New Subcortical Pathological Pathway?

CONCLUSIONS: Our data suggest that H63D polymorphism could represent a disease-modifying gene in FTLD, fostering iron deposition in the basal ganglia. This suggests a new possible mechanism of FTLD-associated neurodegeneration. PMID: 26613252 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26613252?dopt=Abstract

Source: Neuro-Degenerative Diseases - November 28, 2015 Category: Neurology Authors: Gazzina S, Premi E, Zanella I, Biasiotto G, Archetti S, Cosseddu M, Scarpini E, Galimberti D, Serpente M, Gasparotti R, Padovani A, Borroni B Tags: Neurodegener Dis Source Type: research