Follicle-stimulating hormone induces postmenopausal dyslipidemia through inhibiting hepatic cholesterol metabolism.

CONCLUSIONS: FSH may interact with its receptors in hepatocytes and reduce LDLR levels, which subsequently attenuates the endocytosis of LDL-C, resulting in an elevated circulating LDL-C level.
PMID: 26583582 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - November 19, 2015 Category: Endocrinology Authors: Song Y, Wang ES, Xing LL, Shi S, Qu F, Zhang D, Li JY, Shu J, Meng Y, Sheng JZ, Zhou JH, Huang HF Tags: J Clin Endocrinol Metab Source Type: research