Change in a single DNA base drives a childhood cancer

(Children's Hospital of Philadelphia) Pediatric oncology researchers have pinpointed a crucial change in a single DNA base that both predisposes children to an aggressive form of the childhood cancer neuroblastoma and makes the disease progress once tumors form. The gene change results in a 'super enhancer' that drives the cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news