Effects of Developmental Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Long-Term Self-Renewal of Murine Hematopoietic Stem Cells
Conclusions: Our findings indicate that AHR activation by TCDD in the fetus during pregnancy leads to impairment of long-term self-renewal of hematopoietic stem cells.
This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process.
Citation: Laiosa MD, Tate ER, Ahrenhoerster LS, Chen Y, Wang D. Effects of Developmental Activation of the Aryl Hydrocarbon Receptor by 2,3,7,8-Tetrachlorodibenzo-p-dioxin on Long-Term Self-Renewal of Murine Hematopoietic Stem Cells. Environ Health Perspect; http://dx.doi.org/10.1289/ehp.1509820
Received: 12 February 2015
Accepted: 15 October 2015
Advance Publication: 23 October 2015
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Source: EHP Research - Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research
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