Cost-Effectiveness of Conjugate Pneumococcal Vaccination In Croatia

The objective of this study is to estimate the potential effectiveness and cost-effectiveness of vaccinating infants with the pneumococcal non-typeable Haemophilus influenzae Protein D conjugate vaccine (PHiD-CV) compared to the 13-valent pneumococcal conjugate vaccine (PCV-13) in Croatia. These vaccines are currently available only for risk groups and on private market with a limited uptake, representing less than 10% of annual birth cohort.
Source: Value in Health - Category: Global & Universal Authors: Source Type: research

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CONCLUSION: Vaccine-related anaphylaxis seems to have been very rare in the past, but health care professionals must always be aware of anaphylaxis. PMID: 32989932 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
CONCLUSION: After outpatient episode incidence of influenza, antiviral treatment has been shown to reduce the incidence of hospitalized pneumonia, especially in infants and children, during pandemic season 2017. Antiviral therapy for influenza is recommended to minimize burden caused by influenza virus infection and to reduce pneumonia. In addition, medical costs of hospitalization may decrease by antiviral therapy, especially in infants and children. PMID: 32989929 [PubMed - in process]
Source: Journal of Korean Medical Science - Category: Biomedical Science Tags: J Korean Med Sci Source Type: research
Conclusions: The trends observed indicate that the effects of COVID-19 are not only related to the biological characteristics of SARS-CoV-2, but also to the resources (or lack thereof) to deal with it, which are distributed by social processes. PMID: 32983234 [PubMed]
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
Conclusions: A recommendation by a health care provider may be not enough to motivate Latina immigrant mothers to vaccinate their daughters. Further efforts should focus on increasing awareness regarding HPV and cervical cancer, heightening perceived risk of HPV infection among daughters and boosting self-efficacy to get their children vaccinated against HPV. PMID: 32989366 [PubMed - in process]
Source: Ethnicity and Disease - Category: International Medicine & Public Health Tags: Ethn Dis Source Type: research
Trial shows‘robust’ immune response; warning overglobal impact of travel collapse;Belgium death toll exceeds 10,000World Bank announces $12bn plan for vaccines for poor countries‘Only time will tell’: Russia places huge bet on Covid vaccineGermans embrace fresh air to tackle coronavirusIsrael bans mass protests as Covid lockdown tightensUK coronavirus updates – live3.48pmBSTKenya ’s auditor general says the country stands to lose $21 million in the procurement of COVID-19 medical supplies because the Kenya Medical Supplies Agency failed to follow procurement law.General Nancy Gathangu on...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news UK news Science Infectious diseases US news Australia news Microbiology Medical research Source Type: news
In this study, we determined the relationship between binding of IgG or IgM and the bacterial survival in normal human serum for 267 invasive H. influenzae strains from Spain, Portugal, and the Netherlands, of which the majority (200 [75%]) were NTHi. NTHi bacteria opsonized with high levels of IgM had the lowest survival in human serum. IgM binding to the bacterial surface, but not IgG binding, was shown to be associated with complement-mediated killing of NTHi strains. We conclude that evasion of IgM binding by NTHi strains increases survival in blood, thereby potentially contributing to their ability to cause severe invasive diseases.
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Molecular Pathogenesis Source Type: research
ConclusionsAny difference in price between PHiD-CV and PCV13 is expected to be the key driver of vaccine choice for preventing childhood pneumococcal disease in Turkey. At price parity, PHiD-CV use is likely to be a dominant strategy over the use of PCV13.
Source: Value in Health Regional Issues - Category: International Medicine & Public Health Source Type: research
CONCLUSION: The results from this study suggest that our NTHi AOM coinfection model is useful for assessing protein vaccines. PMID: 30136923 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
CONCLUSION: Non-typeable H. influenzae (NTHi), mostly derived from pneumonia and AOM, were genetically diverse, in contrast to the predominance of H. influenzae type b (Hib) among meningitis cases. The associations between certain STs and β-lactam resistance among NTHi were confirmed. PMID: 29595417 [PubMed - as supplied by publisher]
Source: Journal of Medical Microbiology - Category: Microbiology Authors: Tags: J Med Microbiol Source Type: research
Authors: K L Ç H, Akyol S, Parkan ÕM, Dinç G, Sav H, Aydemir G Abstract Haemophilus influenzae can cause invasive and severe infections in both adults and children such as otitis media, sinusitis, pneumonia, meningitis and bacteremia. The emerging antibiotic resistance in recent years against ampicillin and several other antibiotics among strains of H. influenzae gives cause for serious concern. Here, we investigate ß-lactamase (BL) activity in clinical isolates of H. influenzae, profile their resistance to antibiotics, and characterize the clonal relationship of the isolates. Antibiotic ...
Source: Infezioni in Medicina - Category: Infectious Diseases Tags: Infez Med Source Type: research
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