MicroRNA-150 inhibits expression of adiponectin receptor 2 and is a potential therapeutic target in patients with chronic heart failure

Conclusions: MicroRNA-150 counteracts ADIPOR2 up-regulation in CHF and thus may contribute to adiponectin resistance. Targeting microRNA-150 may be a future strategy to restore cardioprotective adiponectin effects.

Source: The Journal of Heart and Lung Transplantation - October 28, 2013 Category: Transplant Surgery Authors: Simone Kreth, Carola Ledderose, Stefanie Schütz, Andres Beiras, Jens Heyn, Florian Weis, Andres Beiras-Fernandez Tags: Featured Articles Source Type: research