This Test Might Tell You If You Don't Need A Statin

Medical tests usually tell you and your doctor if you need to consider taking a medication or having a procedure. It is unusual to think about a test as a way to avoid taking a medication. But I was senior author on a study that showed just that for the decision about whether to take a statin drug, the type of cholesterol-lowering medicine taken by millions of patients. The test is a heart CT scan looking for calcium in the coronary arteries, the major blood vessels that supply the heart.
Source: Healthcare News - Category: Pharmaceuticals Authors: Source Type: news

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Authors: Kumar NS, Basu S Abstract The classical bone scan findings of Rhabdomyolysis is presented in this illustration. A 60 year old female patient with complaints of low backache and bilateral lower limbs weakness over 1 year was referred for whole body skeletal status evaluation. Whole body skeletal scintigraphy undertaken 3 hrs after I.V injection of 15 mci of 99mTc-MDP revealed bilaterally symmetrical diffuse skeletal muscle tracer activity in deltoid, lattisimus dorsi, diaphragm, paraspinal muscles, gluteus muscles and muscles of thigh. On biochemical investigations for evaluation of skeletal muscle uptake r...
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
This study suggests that oral statin therapy may be a new approach for patients with autoimmune pulmonary alveolar proteinosis.AUTHORSThe study ’s co-senior authors are Dr. Elizabeth Tarling of UCLA and Dr. Bruce Trapnell of Children’s Hospital Medical Center of Cincinnati, Ohio. Other authors are listed in the journal article.JOURNALThe study was  published in the journal Nature Communications. FUNDINGThe National Institutes of Health funded the research.Learn more about the  cardiovascular research theme at UCLA. 
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Abstract BACKGROUND: Asian patients with acute coronary syndrome (ACS) are frequently prescribed moderate-intensity statin in real practice, even during the early stage of ACS. Under assessment herein was the effect of moderate-intensity statin therapy on the resolution of plaque inflammation during the first month after ACS, a period with highest recurrent ischemic events, using dual time point ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT). METHODS: This prospective study included statin-naïve patients with ACS and non-calcified carotid plaques (³ 3 mm ...
Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
This week influential Editor-in-Chief ofJAMA Internal Medicine Dr Rita Redberg joins host Ray Moynihan on Cochrane Australia's podcastThe Recommended Dose to share a wide ranging conversation on all things health. A Professor at the University of California San Francisco and high profile contributor to The Washington Post and New York Times, Rita is also a practising cardiologist who loves to see patients. She says that ‘being a doctor is really a privilege’.Together, Ray and Rita canvas many topics including shared decision making between doctors and patients, the tricky territory of medical device a...
Source: Cochrane News and Events - Category: Information Technology Authors: Source Type: news
Authors: Choo EH, Han EJ, Kim CJ, Kim SH, O JH, Chang K, Seung KB Abstract BACKGROUND AND OBJECTIVES: Non-statin therapy plus lower intensity statin might be an alternative in patients with coronary artery disease (CAD). A recent data suggested an anti-inflammatory therapy can reduce recurrent cardiovascular events and pioglitazone is also an intriguing inflammatory-modulating agent. However, limited data exist on whether pioglitazone on top of statins further attenuates plaque inflammation. METHODS: Statin-naïve patients with stable CAD and carotid plaques of ≥3 mm were randomly prescribed moderate dos...
Source: Korean Circulation Journal - Category: Cardiology Tags: Korean Circ J Source Type: research
I was recently invited to speak at David Wolfe’s Longevity NOW conference in Anaheim, California, where I gave a talk entitled “Germs, Muscle, and Pac-Man: New Strategies for Turning the Clock Back 10 or 20 Years” detailing some new strategies for maintaining youthfulness and vigor. (It was a longevity conference, after all. I shall be posting a similar talk on our Undoctored Inner Circle website in the next few days.) Of the 40-some vendor booths that were part of the conference, there was one that caught my eye: O’NA HealthCare. They claim to provide coverage for functional medicine care, integrat...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Undoctored Wheat Belly Lifestyle health insurance healthcare low-cost Source Type: blogs
A sixty-one-year-old man with a history of hyperlipidaemia, arterial hypertension, positive family history, smoking, and atypical angina pectoris was referred for investigation of coronary artery disease. (Panel A) Coronary computed tomography angiography (CCTA) revealed a non-stenotic atherosclerotic plaque located in the left main (LM) and the proximal left anterior descending artery (pLAD), exhibiting high-risk plaque features including napkin-ring sign, low attenuation, and positive external remodelling. Non-stenotic calcified lesions were also found in the mid-LAD and proximal right coronary artery. (Panel B) The pati...
Source: European Heart Journal - Category: Cardiology Source Type: research
ObjectiveTo assess the effect of tumor necrosis factor inhibitors (TNFi) on subclinical cardiovascular disease in patients with psoriatic disease. MethodsWe performed a 2‐stage study. In stage 1, carotid total plaque area was assessed in patients with psoriasis or psoriatic arthritis (PsA) (n = 319) by ultrasound at baseline and after 2–3 years. The annual progression rate of atherosclerosis was the outcome of interest. In stage 2, PsA patients receiving TNFi (n = 21) and age‐ and sex‐matched PsA patients not receiving any biologic agent (n = 13) underwent 18F‐fluorodeoxyglucose–positron emission tomogr...
Source: Arthritis and Rheumatism - Category: Rheumatology Authors: Tags: Original Article Source Type: research
Conclusion Acetylsalicylic acid use is associated with decreased thrombus sac volume in a patient population undergoing elective abdominal aortic aneurysms repair. The effect of acetylsalicylic acid over other anti-inflammatory and anti-platelet agents is possibly attributable to its distinct mechanism of cyclooxygenase-1 inhibition. Diabetes mellitus, a known correlate of aneurysm incidence, is not associated with thrombus burden. The potential to alter aneurysm thrombus volume, thereby affecting aneurysm morphology, may yield a more favorable aneurysmal repair. PMID: 29473449 [PubMed - as supplied by publisher]
Source: Vascular - Category: Surgery Authors: Tags: Vascular Source Type: research
ConclusionMonocyte CCR2 expression is associated with arterial wall inflammation in patients at increased cardiovascular risk. Our data warrant further studies to assess if inhibition of CCR2 may attenuate atherosclerotic plaque inflammation.
Source: Cardiovascular Research - Category: Cardiology Source Type: research
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