Uninterrupted new oral anticoagulants compared to uninterrupted Vitamin K antagonists in ablation of atrial fibrillation. A Meta-analysis

Conclusion Use of uninterrupted NOAC in ablation appears to be as safe and efficacious as uninterrupted VKA. Teaser This meta-analysis compares uninterrupted non vitamin K antagonists (NOAC) with uninterrupted vitamin K antagonists (VKA) in ablation of atrial fibrillation. A total of 3544 patients undergoing ablation with uninterrupted anticoagulation. Overall incidence of stroke/TIA was very low 0.16%, major bleeding was 0.5% and only once case of death reported in the uninterrupted VKA arm. Uninterrupted NOAC appears as safe as uninterrupted VKA with no difference in stroke/TIA, major bleeding, minor bleeding or cardiac tamponade.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research