Effect of statins on aortic root growth rate in patients with bicuspid aortic valve anatomy

In conclusion, in patients with BAV, although the use of statins was associated with smaller ascending aorta, the annual dilation rate of the aortic root was not influenced by the use of statins.
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research

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Women who naturally exhibit lower levels of an enzyme blocked by statins have an estimated 40 per cent lower risk of ovarian cancer, a study by Bristol University found.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
This study aimed to explore the cardiologist adherence with ACC/AHA guidelines on discharge medications for patients admitted with acute coronary syndrome (ACS), assess the predictors of cardiologist non-adherence and measure the impact of pharmacist intervention on improving guideline adherence.MethodsThe study included two consecutive phases: observation and intervention. It was carried out at Al-Najaf Center for Cardiac Surgery and Catheterization, Iraq, from August through December 2018. In the observation phase, medical records were reviewed retrospectively in order to assess the adherence to guideline. The interventi...
Source: Saudi Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
In the UK, ovarian cancer is the sixth most common cancer in females*. A new study has found evidence to suggest that statins could lower the risk of women developing ovarian cancer. The research led by the University of Bristol, and funded by Cancer Research UK, is published today [18 February] in JAMA.
Source: University of Bristol news - Category: Universities & Medical Training Tags: Health, Research, International; Faculty of Health Sciences, Faculty of Health Sciences, Bristol Medical School, Institutes, Bristol Population Health Science Institute; Press Release Source Type: news
The 2016 review for the US Preventive Services Task Force on statins for prevention of cardiovascular disease in adults had errors in the analysis of statins vs placebo and cardiovascular mortality. For the JUPITER trial, we interpreted “MI, stroke or cardiovascular death” as reported in the main trial publication as “myocardial death, stroke death, or cardiovascular death,” when it meant “nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death.” Therefore, the analysis erroneously included nonfatal myo cardial infarction and stroke events (83/8901 vs 157/8901 in the ros...
Source: JAMA - Category: General Medicine Source Type: research
This article was corrected online.
Source: JAMA - Category: General Medicine Source Type: research
This article was corrected online.
Source: JAMA - Category: General Medicine Source Type: research
In the US Preventive Services Task Force (USPSTF) Recommendation Statement entitled “Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: US Preventive Services Task Force Recommendation Statement” published in the November 15, 2016, issue of JAMA, incorrect data were reported in the text. In the first paragraph of the “Statin Use in Adults Aged 40 to 75 Years” subsection and in the third paragraph of the “Benefits of Statin Use” subsection, the text “RR, 0.69 [95% CI, 0.54-0.88]” should have read “RR, 0.82 [95% CI, 0.71-0.94].” The certainty...
Source: JAMA - Category: General Medicine Source Type: research
An 85-year-old man presented with left hemiparesis, too late for any intervention. Brain computed tomography (CT) revealed a right hemispheric infarct. He had a history of diabetes mellitus (on metformin, statin), hypertension (on losartan/lercanidipine), past smoking, COPD (on inhalers) and peripheral artery disease (on aspirin).
Source: The American Journal of Medicine - Category: General Medicine Authors: Tags: Clinical Communication to the Editor Source Type: research
DiscussionIn hindsight I feel there are very few alternative causes for an ECG like this other than an acute LAD occlusion. I believe this is one of those'subtle STEMI'cases where neither the ECG nor the symptoms are very obvious or severe and the usual evolution is not seen.I think of these cases as'insidious infarcts'and I have seen this in all infarct territories and I do not think they are particularly rare. Essentially the patient is fairly comfortable and the ECG is not obvious but the patient ended up with Q waves, huge troponins and we missed the opportunity to reperfuse the artery when it counts. These patients te...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
AbstractIntroductionEzetimibe/statin combination therapy has been reported to provide additional cardioprotective effects compared to statin monotherapy. The apolipoprotein B/A1 (apoB/A1) ratio is an effective predictor of cardiovascular diseases. The aim of this study was to compare the efficacy and safety of rosuvastatin/ezetimibe combination therapy versus rosuvastatin monotherapy using the apoB/A1 ratio in patients with diabetes and hypercholesterolemia.MethodsIn this randomized, multicenter, open-label, parallel-group study, patients were randomly assigned to receive the combination therapy of rosuvastatin 5  mg/...
Source: Diabetes Therapy - Category: Endocrinology Source Type: research
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