Coagulation factor XII genetic variation, ex vivo thrombin generation, and stroke risk in the elderly: results from the Cardiovascular Health Study.

CONCLUSIONS: These results support the importance of contact activation pathway-dependent TG as a risk factor for ischemic stroke and indicate the importance of F12 SNPs on TG ex vivo and in vivo. This article is protected by copyright. All rights reserved.
PMID: 26286125 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - August 19, 2015 Category: Hematology Authors: Olson NC, Butenas S, Lange LA, Lange EM, Cushman M, Jenny NS, Walston J, Souto JC, Soria JM, Chauhan G, Debette S, Longstreth WT, Seshadri S, Reiner AP, Tracy RP Tags: J Thromb Haemost Source Type: research