Aggravated restenosis and atherogenesis in ApoCIII transgenic mice but lack of protection in ApoCIII knockouts: the effect of authentic triglyceride-rich lipoproteins with and without ApoCIII

Conclusions
Severe hypertriglyceridaemia resulting from ApoCIII overexpression promotes restenosis and atherosclerosis. Furthermore, we demonstrated that TRLs + ApoCIII promotes SMC proliferation.

Source: Cardiovascular Research - August 18, 2015 Category: Cardiology Authors: Li, H., Han, Y., Qi, R., Wang, Y., Zhang, X., Yu, M., Tang, Y., Wang, M., Shu, Y.-N., Huang, W., Liu, X., Rodrigues, B., Han, M., Liu, G. Tags: Vascular biology Source Type: research