Thromboxane A2 induces blood flow recovery via platelet adhesion to ischaemic regions
Conclusion
These results indicated that TP signalling facilitates ischaemia-induced angiogenesis via P-selectin-mediated platelet adhesion to PSGL-1 on the ECs at ischaemic sites and the supply of pro-angiogenic factors by the adherent platelets.
Source: Cardiovascular Research - Category: Cardiology Authors: Amano, H., Ito, Y., Eshima, K., Kato, S., Ogawa, F., Hosono, K., Oba, K., Tamaki, H., Sakagami, H., Shibuya, M., Narumiya, S., Majima, M. Tags: Vascular biology Source Type: research