Acquired Tumor Cell Radiation Resistance at the Treatment Site Is Mediated Through Radiation-Orchestrated Intercellular Communication

Conclusions: Together, these data strongly suggest that scattered LDIR-induced NFκB-dependent TNF-α, IL-1α, cMYC, and SOD2 mediate radiation protection to the subsequent challenge dose in tumor cells.

Source: International Journal of Radiation Oncology * Biology * Physics - January 8, 2014 Category: Radiology Authors: Natarajan Aravindan, Sheeja Aravindan, Vijayabaskar Pandian, Faizan H. Khan, Satish Kumar Ramraj, Praveen Natt, Mohan Natarajan Tags: Biology Contributions Source Type: research