Antibiotic Resistance of Campylobacter jejuni and C. coli Isolated from Children with Diarrhea in Thailand and Japan.

Antibiotic Resistance of Campylobacter jejuni and C. coli Isolated from Children with Diarrhea in Thailand and Japan.
Jpn J Infect Dis. 2015 Jul 10;
Authors: Pham NT, Thongprachum A, Tran DN, Nishimura S, Shimizu-Onda Y, Trinh QD, Khamrin P, Ukarapol N, Kongsricharoern T, Komine-Aizawa S, Okitsu S, Maneekarn N, Hayakawa S, Ushijima H
Abstract
Twenty nine Campylobacter jejuni and C. coli strains detected from Thai and Japanese children with diarrhea by Loop-mediated Isothermal Amplification method were analyzed to investigate the resistance against fluoroquinolones and macrolides by studying the mutations in the gyrA and 23S rRNA genes, respectively. Of these, 9 strains (8 C. jejuni and 1 C. coli) were from Thai children, and the other 20 C. jejuni strains were from Japanese children. The result showed that high fluoroquinolone resistance rates continued to be found in Thailand (66.7%) and Japan (90%). Macrolide resistance was not noted in Japan in this study, however, it was observed in a considerable rate of 12.5% of C. jejuni isolated in Thailand. Continuing to monitor the resistance to fluoroquinolones and macrolides of Campylobacter is definitely necessary.
PMID: 26166497 [PubMed - as supplied by publisher]

Source: Japanese Journal of Infectious Diseases - July 10, 2015 Category: Infectious Diseases Authors: Pham NT, Thongprachum A, Tran DN, Nishimura S, Shimizu-Onda Y, Trinh QD, Khamrin P, Ukarapol N, Kongsricharoern T, Komine-Aizawa S, Okitsu S, Maneekarn N, Hayakawa S, Ushijima H Tags: Jpn J Infect Dis Source Type: research