Safety and immunogenicity of a trivalent recombinant PcpA, PhtD, and PlyD1 pneumococcal protein vaccine in adults, toddlers, and infants: A phase I randomized controlled study.
CONCLUSIONS: The candidate trivalent PPrV was safe and immunogenic in adults, toddlers, and infants. Addition of aluminum adjuvant improved immunogenicity in infants without changing the safety profile.
PMID: 26143615 [PubMed - as supplied by publisher]
Source: Vaccine - Category: Allergy & Immunology Authors: Brooks WA, Chang LJ, Sheng X, Hopfer R, PPR02 Study Team Tags: Vaccine Source Type: research
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