Inhibition of ADORA3 promotes microglial phagocytosis and alleviates chronic ischemic white matter injury

CONCLUSIONS: ADORA3 antagonist alleviates chronic ischemic WMI by modulating myelin clearance of microglia, which may be a potential therapeutic target for the treatment of VaD.PMID:38715283 | DOI:10.1111/cns.14742

Source: CNS Neuroscience and Therapeutics - May 8, 2024 Category: Neuroscience Authors: Yuhao Xu Limoran Tang Chao Zhou Liang Sun Yujie Hu Zhi Zhang Shengnan Xia Xinyu Bao Haiyan Yang Yun Xu Source Type: research