Enhanced hepatotoxicity in zebrafish due to co-exposure of microplastics and sulfamethoxazole: Insights into ROS-mediated MAPK signaling pathway regulation

In conclusion, our findings suggest that co-exposure to SMZ and MPs induces hepatic dysfunction through the ROS-mediated MAPK signaling pathway in zebrafish. This information provides novel insights into the potential environmental risk of MPs and hazardous pollutants co-existence in aquatic ecosystems.PMID:38703406 | DOI:10.1016/j.ecoenv.2024.116415

Source: Ecotoxicology and Environmental Safety - May 4, 2024 Category: Environmental Health Authors: Guanghua Xiong Haiyan Zhang Huangqi Shi Yulin Peng Meiling Han Tianle Hu Xinjun Liao Yong Liu Jun'e Zhang Gaoxiao Xu Source Type: research