Ovarian reserve in patients with FMR1 gene premutation and the role of fertility preservation

CONCLUSIONS: This study shows the importance of early fertility preservation after diagnosis of FMR1 premutation in women, due to early deterioration of ovarian reserve. Genetic counseling is essential in these patients, as spontaneous pregnancies are not uncommon, even in cases of impaired ovarian reserve, and can lead to birth of affected children.PMID:38702011 | DOI:10.1016/j.ando.2024.04.004

Source: Annales d'Endocrinologie - May 3, 2024 Category: Endocrinology Authors: Tiphaine Le Poulennec Sophie Dubreuil Michael Grynberg Nathalie Chabbert-Buffet Nathalie Sermondade Salma Fourati Jean-Pierre Siffroi Delphine H éron Anne Bachelot Source Type: research