Comprehensive Genomic Characterization in Ovarian Low-Grade and chemosensitive and chemoresistant High-Grade Serous Carcinomas

CONCLUSIONS: These results suggest that very low TMB and MYC, CCNE1 and AKT2 gains in SOC patients may be biomarkers related to platinum treatment efficacy. Thorough genomic characterization of SOCs prior to treatment might lead to more specific platinum-based chemotherapy therapy strategies.PMID:38697030 | DOI:10.1159/000538948

Source: Oncology - May 2, 2024 Category: Cancer & Oncology Authors: Carolina Jaliffa Uwe Rogel Indrani Sen Gad Singer Source Type: research