Germline findings in cancer predisposing genes from a small cohort of chordoma patients

CONCLUSION: We report here a chordoma cohort of 24 families with newly found germline genetic mutations in cancer predisposing genes. We discuss implications for genetic counseling, clinical management, and universal germline genetic testing for cancer patients with solid tumors.PMID:38700789 | DOI:10.1007/s00432-024-05706-5

Source: Clin Med Res - May 3, 2024 Category: Research Authors: Margarita Raygada Liny John Anne Liu Julianne Schultz B J Thomas Donna Bernstein Markku Miettinen Mark Raffeld Liqiang Xi Manoj Tyagi Kenneth Aldape John Glod Karlyne M Reilly Brigitte C Widemann Mary Frances Wedekind Source Type: research