Computational Screening of Some Phytochemicals to Identify Best Modulators for Ligand Binding Domain of Estrogen Receptor Alpha

CONCLUSION: Additionally, these compounds are being reported for the first time in this study as possible inhibitors of ERα for treating breast cancer, according to the notion of drug repurposing. Hence, these phytochemicals can be further studied and used as a parent core molecule to develop innovative lead molecules for breast cancer therapy.PMID:38698754 | DOI:10.2174/0113816128287431240408045732

Source: Current Pharmaceutical Design - May 3, 2024 Category: Drugs & Pharmacology Authors: Veerachamy Alagarsamy P Shyam Sundar Viswas Raja Solomon Sankaranarayanan Murugesan Mohammed Muzaffar-Ur-Rehman Vishaka Sumant Kulkarni Mohaideen Thasthagir Sulthana Bandi Narendhar Govindraj Sabarees Source Type: research