Aminophylline Improves Ventilator-Induced Diaphragmatic Dysfunction by Targeting IGF-1-FOXO1-MURF1 Pathway

CONCLUSIONS: In this study, MV treatment induced symptoms of VIDD in rats, which were all effectively reversed by AP regulating the IGF-1-FOXO1-MURF1 pathway, demonstrating the potential of AP in ameliorating VIDD.PMID:38665019 | DOI:10.24976/Discov.Med.202436183.66

Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Luyu Yang Xiaohong Jiang Jinhui Tan Shouzhi Fu Wankang Dian Source Type: research