Activation of M2 macrophage autophagy by rapamycin increases the radiosensitivity of colorectal cancer xenografts

CONCLUSIONS: Therefore, autophagy-activated M2 supernatant can downregulate the expression of the antiapoptotic genes Livin and Survivin in CRC xenografts, improving the radiosensitivity of CRC by inducing apoptosis in combination with radiotherapy and inhibiting the growth of transplanted tumors.PMID:38687942 | DOI:10.4103/jcrt.jcrt_215_23
Source: Cancer Control - Category: Cancer & Oncology Authors: Source Type: research