Changes and Significance of Central Carbon Metabolism before and after Metformin Treatment of Type 2 Diabetes Based on Mass Spectrometry

CONCLUSIONS: We employed HPIC-MS/MS to uncover alterations in CCM among individuals recently diagnosed with T2D before and after metformin treatment. The findings suggest that metformin may ameliorate the energy metabolism imbalance in T2D by reducing intermediates within the CCM pathway.PMID:38665017 | DOI:10.24976/Discov.Med.202436183.64

Source: Discovery Medicine - April 26, 2024 Category: Research Authors: Yang Shu Fujie Yang Weidong Li Lisha Li Qiongying Hu Daqian Xiong Source Type: research