A high performance liquid chromatography - Tandem mass spectrometry assay for therapeutic drug monitoring of 10 drug compounds commonly used for antimicrobial therapy in plasma and serum of critically ill patients: Method optimization, validation, cross-validation and clinical application

CONCLUSION: The established multiplex method covers major drug classes with documented dosing challenges, provides a reliable basis for the implementation of high-throughput TDM, and its application confirmed the clinical impact of TDM in a real-world setting.PMID:38677452 | DOI:10.1016/j.cca.2024.119690
Source: International Journal of Clinical Chemistry - Category: Chemistry Authors: Source Type: research