Ginsenoside Rb1 ameliorates lipotoxicity-induced myocardial injury in diabetes mellitus by regulating Mfn2

CONCLUSION: GRb1 alleviated myocardial lipid accumulation and mitochondrial injury, and attenuated ventricular diastolic dysfunction in diabetic mice. The regulation of Mfn2 was involved in the protective effects of GRb1 against lipotoxic myocardial injury.PMID:38677536 | DOI:10.1016/j.ejphar.2024.176609

Source: European Journal of Pharmacology - April 27, 2024 Category: Drugs & Pharmacology Authors: Louyin Ji Hui Han Xiaoli Shan Pei Zhao Huihua Chen Chen Zhang Ming Xu Rong Lu Wei Guo Source Type: research