Tenascin C activates the toll ‑like receptor 4/NF‑κB signaling pathway to promote the development of polycystic ovary syndrome

In conclusion, knockdown of TNC could ameliorate PCOS in both rats and a cell model by inhibiting cell apoptosis, oxidative stress and inflammation via the suppression of the TLR4/NF‑κB signaling pathway.PMID:38666538 | DOI:10.3892/mmr.2024.13230

Source: Molecular Medicine - April 26, 2024 Category: Molecular Biology Authors: Han Wu Mo Yang Cuiping Yan Mengchen Liu Haoran Wang Wenjuan Zhang Source Type: research