Renin-angiotensin system inhibitor use and risk of Parkinson ’s disease: a meta-analysis

ConclusionOverall, RAS inhibitor use as a class is associated with a reduction in PD risk. However, the findings of ACEIs and ARBs may be limited by small sample size. Future well-designed studies considering the classification by inhibitor type, duration, dose, or property of BBB penetration of RAS inhibitors are needed to clarify the contribution of these exposure parameters on the risk of PD.
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research