Blocking group 2 innate lymphoid cell activation and macrophage M2 polarization: potential therapeutic mechanisms in ovalbumin-induced allergic asthma by calycosin

CONCLUSIONS: Collectively, this study showed that calycosin might attenuate OVA-induced airway inflammation and remodeling in asthmatic mice via preventing ILC2 activation and macrophage M2 polarization. Our study might contribute to further study of asthmatic therapy.PMID:38650035 | PMC:PMC11036756 | DOI:10.1186/s40360-024-00751-9
Source: BMC Pharmacology and Toxicology - Category: Drugs & Pharmacology Authors: Source Type: research