Non-specific effects of the inactivated influenza vaccine. A test-negative study: The inactivated influenza vaccine and SARS-CoV-2 infections

CONCLUSIONS: While earlier observational studies suggested a protective non-specific effect of IIV and SARS-CoV-2 infections, this smaller, but well controlled test-negative design study does not suggest an effect, either positive or negative. Larger test-negative design studies, or alternative designs such as the self-controlled case series design are needed to confirm these findings and provide more definite answers on the topic.PMID:38658205 | DOI:10.1016/j.vaccine.2024.04.044

Source: Vaccine - April 24, 2024 Category: Allergy & Immunology Authors: Anne Jasmijn Sellies Mirjam J Knol Hester E de Melker Patricia C J L Bruijning-Verhagen Annemarijn R de Boer Source Type: research