The IFT80/Hedgehog Pathway Regulates the Osteogenic-adipogenic Differentiation of Bone Marrow Mesenchymal Stem Cells

CONCLUSION: There is a dysregulation of the balance of osteogenic-adipogenic differentiation in SANFH. IFT80 may inhibit adipogenic differentiation while promoting osteogenic differentiation in rabbit BM-MSCs by activating the Hedgehog pathway.PMID:38644709 | DOI:10.2174/0109298673300113240418050128

Source: Current Medicinal Chemistry - April 22, 2024 Category: Chemistry Authors: Mingyang Jiang Ke Zhang Yang Hu Shenyi Lu Guiqing Wei Kaicheng Liu Chuanliang Chen Xiaochong Zou Yongheng Dai Ying Gui Jing Wu Huan Bo Zhandong Bo Source Type: research