Di-n-butyl phthalate induces toxicity in male fetal mouse testicular development by regulating the MAPK signaling pathway

In conclusion, our study provides the first evidence that the MAPK signaling pathway is involved in DBP-induced reproductive toxicity and highlights the importance of JNK1 as a potential target of DBP in inducing reproductive toxicity.PMID:38631520 | DOI:10.1016/j.taap.2024.116933

Source: Toxicology and Applied Pharmacology - April 17, 2024 Category: Toxicology Authors: Xinwei Wan Xudong Cui Xiang Wang Mingyang Feng Shinan Wei Jia Yu Sha Cheng Heng Luo Jianxin Hu Source Type: research