The mitochondria-targeted antioxidant MitoQ ameliorates inorganic arsenic-induced DCs/Th1/Th2/Th17/Treg differentiation partially by activating PINK1-mediated mitophagy in murine liver
This study has provided new insights on the immunotoxicity of inorganic arsenic and established a foundation for exploring preventive and therapeutic strategies targeting PINK1-mediated mitophagy in acute liver injury. Consequently, the application of mitochondrial antioxidant MitoQ may offer a promising treatment for the metalloid-induced acute liver injury.PMID:38653026 | DOI:10.1016/j.ecoenv.2024.116350
Source: Ecotoxicology and Environmental Safety - Category: Environmental Health Authors: Hui Li Yaning Guo Wei Su Huan Zhang Xiaoxi Wei Xinyu Ma Shuwen Gong Gaoyang Qu Lin Zhang Hong Xu Fuhai Shen Shoufang Jiang Dingjie Xu Jinlong Li Source Type: research
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