In Vivo Measurement of GABA Transmission in Healthy Subjects and Schizophrenia Patients.

CONCLUSIONS: This study demonstrates, for the first time, an in vivo impairment in GABA transmission in schizophrenia, most prominent in antipsychotic-naive individuals. The impairment in GABA transmission appears to be linked to clinical symptoms, disturbances in cortical oscillations, and cognition. PMID: 26133962 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26133962?dopt=Abstract

Source: The American Journal of Psychiatry - July 2, 2015 Category: Psychiatry Authors: Frankle WG, Cho RY, Prasad KM, Mason NS, Paris J, Himes ML, Walker C, Lewis DA, Narendran R Tags: Am J Psychiatry Source Type: research