Radio-Guided Surgery with a New-Generation β-Probe for Radiolabeled Somatostatin Analog, in Patients with Small Intestinal Neuroendocrine Tumors

CONCLUSION: This study reports optimal accuracy in detecting lesions of SI-NETs using the intraoperative RGS approach with a novel β-probe. The method was found to be safe, feasible, and easily reproducible in daily clinical practice, with minimal radiation exposure for the staff. RGS might potentially improve radical resection rates in SI-NETs.CLINICAL TRIALS REGISTRATION: 68Ga-DOTATOC Radio-Guided Surgery with β-Probe in GEP-NET (RGS GEP-NET) [NCT0544815; https://classic.CLINICALTRIALS: gov/ct2/show/NCT05448157 ].PMID:38652200 | DOI:10.1245/s10434-024-15277-x

Source: Ann Oncol - April 23, 2024 Category: Cancer & Oncology Authors: Emilio Bertani Francesco Mattana Francesco Collamati Mahila E Ferrari Vincenzo Bagnardi Samuele Frassoni Eleonora Pisa Riccardo Mirabelli Silvio Morganti Nicola Fazio Uberto Fumagalli Romario Francesco Ceci Source Type: research