Berberine alleviates neuroinflammation by downregulating NFkB κκNF/LCN2 pathway in sepsis-associated encephalopathy: Network pharmacology, bioinformatics, and experimental validation

CONCLUSION: Overall, Berberine may exert anti-inflammatory effects through multi-ingredients, multi-targets and multi-pathways to partially rescue neuronal death and alleviate SAE.PMID:38640713 | DOI:10.1016/j.intimp.2024.112036

Source: International Immunopharmacology - April 19, 2024 Category: Allergy & Immunology Authors: Hailong Gong Yun Xia Guoqing Jing Min Yuan Huimin Zhou Die Wu Jing Zuo Chuntian Lei Delida Aidebaike Xiaojing Wu Xuemin Song Source Type: research