Ketogenic diet time-dependently prevents NAFLD through upregulating the expression of antioxidant protein metallothionein-2

The past few decades have witnessed a rapid growth in the prevalence of nonalcoholic fatty liver disease (NAFLD). While the ketogenic diet (KD) is considered for managing NAFLD, the safety and efficacy of the KD on NAFLD has been a controversial topic. Here, we aimed to investigate the effect of KD of different durations on metabolic endpoints in mice with NAFLD and explore the underlying mechanisms.

Source: Clinical Nutrition - April 22, 2024 Category: Nutrition Authors: Yuehua You, Yi Huang, Xiaoyang Wang, Hongbin Ni, Qin Ma, Haiying Ran, Jingshu Cai, Xiaojing Lin, Ting Luo, Chaodong Wu, Xiaoqiu Xiao, Li Ma Source Type: research