Correlation of immediate prevalence of cervical precancers and cancers with HPV genotype and age in women with ASC-US/hrHPV+: a retrospective analysis of 2292 cases

Conclusion
Women with ASC-US/hrHPV+ are at significant risk of cervical precancers and cancers; notably, HPV-16+ group has a higher risk of HSIL squamous lesions and SCC while HPV-18/45+ group has a higher risk of AIS+ glandular lesions. In addition, the older patient group (>50 years) has a significantly higher risk of SCC. Therefore, HPV genotyping as well as patient age need to be considered in the clinical management of patient.

Source: Journal of Clinical Pathology - April 18, 2024 Category: Pathology Authors: Liu, Q., Zhang, T., Chen, L., Zhou, X., Zhang, X., Zheng, W., Niu, S., Zhou, F. Tags: Original research Source Type: research