Single-cell transcriptomics reveal metastatic CLDN4+ cancer cells underlying the recurrence of malignant pleural effusion in patients with advanced non-small-cell lung cancer

CONCLUSIONS: CLDN4 could be considered as a predictive marker of recurrent MPE among patients with advanced NSCLC. Further validation for its clinical value in cohorts with larger sample size and in-depth mechanism studies on its biological function are warranted.TRIAL REGISTRATION: Not applicable.PMID:38629624 | DOI:10.1002/ctm2.1649
Source: Clinical Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research