Effectiveness of two and three doses of COVID-19 mRNA vaccines against infection, symptoms, and severity in the pre-omicron era: A time-dependent gradient

CONCLUSION: A gradient in vaccine effectiveness exists and is linked to the symptoms and severity of infection, providing higher protection against more symptomatic and severe cases. This gradient intensifies over time as vaccine immunity wanes after the last vaccine dose. These patterns appear consistent irrespective of the vaccine type or whether the vaccination involves the primary series or a booster.PMID:38616439 | DOI:10.1016/j.vaccine.2024.04.026

Source: Vaccine - April 15, 2024 Category: Allergy & Immunology Authors: Layan Sukik Hiam Chemaitelly Houssein H Ayoub Peter Coyle Patrick Tang Hadi M Yassine Asmaa A Al Thani Mohammad R Hasan Zaina Al-Kanaani Einas Al-Kuwari Andrew Jeremijenko Anvar Hassan Kaleeckal Ali Nizar Latif Riyazuddin Mohammad Shaik Hanan F Abdul-Rahi Source Type: research