The co-occurrence of multiple sclerosis and bipolar disorder: A case series on clinical and neuroimaging correlates

We describe the clinical profile and neuroimaging findings of four cases of MS with BD. Among them, two patients had multiple mood episodes preceding the neurological symptoms, one had concurrent manic and neurological symptoms, and one had multiple depressive episodes and an isolated steroid-induced manic episode. Frontal and temporal lobes, and Periventricular White Matter were involved in all four cases, and hence may be considered biological substrates of BD in MS. Larger studies are needed to validate the utility of these findings.PMID:38615578 | DOI:10.1016/j.ajp.2024.104041

Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Harkishan Mamtani Kshiteeja Jain Preethi Reddy Rashmi Arasappa Sundarnag Ganjekar Harish Thippeswamy Maya Bhat M Netravathi Geetha Desai Source Type: research