Cadherin-17 as a target for the immunoPET of adenocarcinoma

CONCLUSION: Taken together, these data underscore that [89Zr]Zr-DFO-D2101 is a highly promising probe for the non-invasive visualization of CDH17 expression in PDAC. We contend that this radioimmunoconjugate could have a significant impact on the clinical management of patients with both PDAC and gastrointestinal adenocarcinoma, most likely as a theranostic imaging tool in support of CDH17-targeted therapies.PMID:38625402 | DOI:10.1007/s00259-024-06709-7

Source: Molecular Medicine - April 16, 2024 Category: Molecular Biology Authors: Samantha Delaney Outi Kein änen Dennis Lam Andrew L Wolfe Takao Hamakubo Brian M Zeglis Source Type: research