A 78-year-old woman with diffuse white matter infiltration and predominant involvement of bilateral temporo-parieto-occipital regions

J Cell Mol Med. 2024 Apr;28(8):e18245. doi: 10.1111/jcmm.18245.ABSTRACTDiffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype (H3/IDH-wt-pHGG) is a newly defined entity amongst brain tumours, primarily reported in children. It is a rare, ill-defined type of tumour and the only method to diagnose it is DNA methylation profiling. The case we report here carries new knowledge about this tumour which may, in fact, occur in elderly patients, be devoid of evocative genomic abnormalities reported in children and harbour a misleading mutation.PMID:38613356 | PMC:PMC11015387 | DOI:10.1111/jcmm.18245
Source: J Cell Mol Med - Category: Molecular Biology Authors: Source Type: research