Nationwide hospitalizations of patients with down syndrome and congenital heart disease over a 15-year period

Conclusions: A younger age at first admission is a predictor for mortality in patients with Down syndrome and congenital heart disease. If patients undergo more than one admission, the risk of further readmissions increases. There is a pivotal role for heart disease in influencing the hospitalization rate and subsequent mortality.What is Known:•Down syndrome individuals often face an increased risk of congenital heart diseases.•Congenital heart diseases contribute significantly to morbidity and mortality in Down syndrome patients.What is New:•This study analyzes nationwide data covering a 15-year period of pediatric and adult patients in Italy with Down syndrome and congenital heart disease.•It identifies a younger age at first admission as a predictor for mortality in these patients, emphasizing the criticality of early intervention.•Demonstrates a correlation between multiple admissions, particularly those related to cardiac issues, and an increased risk of further readmissions, providing insights into the ongoing healthcare needs of these individuals.
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research