Analysis of the Expression of < em > PRDX6 < /em > in Patients with Hepatocellular Carcinoma and its Effect on the Phenotype of Hepatocellular Carcinoma Cells

CONCLUSION: The expression of PRDX6 may be closely related to the prognosis of HCC. Lentivirus-mediated PRDX6 knockdown can inhibit the proliferation, migration and invasion of HCC cells, which may be related to its regulating the PI3K/Akt/mTOR and Notch1 signaling pathways. PRDX6 is expected to be a new target for the diagnosis and treatment of liver cancer.PMID:38544826 | PMC:PMC10964084 | DOI:10.2174/0113892029273682240111052317

Source: Current Genomics - March 28, 2024 Category: Genetics & Stem Cells Authors: Runhong Mu Mingzhu Chang Chuanbo Feng Yunhe Cui Tingyu Li Chang Liu Yilin Wang Xiao Guo Source Type: research